Our scientists have shared their findings in articles in many of the world's leading
scientific publications. Articles in, peer-reviewed publications provide strong validation
from the scientific community of Maxygen's technologies. After reviewing this list of
selected recent publications, you may request a free reprint by clicking here.
Year: 2008
Year: 2007
Year: 2006
| Author(s) |
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Title |
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Source |
| Apt, D., Raviprakash, K., Brinkman, A., Semyonov, A., Yang, S., Skinner, C., Diehl, L., Lyons, R., Porter, K., Punnonen, J. | | Tetravalent neutralizing antibody response against four dengue serotypes by a single chimeric dengue envelope antigen. | | Vaccine, 24:335-344 | | |
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Year: 2005
| Author(s) |
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Title |
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Source |
| Locher C.P., Paidhungat M., Whalen R.G. and Punnonen J. | | DNA shuffling and screening strategies for improving vaccine efficacy. | | DNA and Cell Biology, April, 24(4): 256-263 | | | | Wright A., Semyonov A., Dawes G., Crameri A., Lyons R., Stemmer WPC, Apt D., Punnonen J. | | Diverse plasmid DNA vectors by directed evolution of cytomegalovirus promoters | | Human Gene Therapy, July 16 (7): 881-892 | | |
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Year: 2004
| Author(s) |
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Title |
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Source |
| Locher C.P., Heinrichs V., Apt, D. and Whalen R.G. | | Overcoming antigenic diversity and improving vaccines using DNA shuffling and screening technologies. | | Expert Opinion on Biological Therapy, April 4(4): 589-597 | | | | Locher, C.P., Soong N.W., Whalen R.G. and Punnonen J. | | Development of novel vaccines using DNA shuffling and screening strategies. | | Current Opinion in Molecular Therapeutics, February, 6(1): 34-39 | | |
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Year: 2003
| Author(s) |
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Title |
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Source |
| Leong, Steven R., Chang, Jean, C.C., Ong, Randal, Dawes, Glenn, Stemmer, Willem P.C., and Punnonen, Juha | | Optimized expression and specific activity of IL-12 by directed molecular evolution | | Proc. Natl. Acad. Sci. USA, Vol. 100, Issue 3, 1163-1168, February 4, 2003 | | |
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Year: 2002
| Author(s) |
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Title |
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Source |
| Lazetic, S., Leong, S., Chang, J.C.C., Ong, R., Dawes, G., Punnonen, J. | | Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells | | Journal of Biological Chemistry, October 11, 277 (41): pp. 38660-38668. | | | | Pekrun K., Shibata R., Igarashi T., Reed M., Sheppard L., Patten P.A., Stemmer W.P.C., Martin M.A. and Soong N.-W. | | Evolution of a human immunodeficiency virus type 1 variant with enhanced replication in pig-tailed macaque cells by DNA Shuffling | | Journal of Virology, March, 76(6): 2924-2935. | | | | Reed M., Mariani R., Sheppard L., Pekrun K., Landau N.R. and Soong N.W. | | Chimeric human immunodeficiency virus type 1 containing murine leukemia virus matrix assembles in murine cells | | Journal of Virology, January, 76(1): 436-443. | | |
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Year: 2001
| Author(s) |
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Title |
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Source |
| Whalen R.G., Kaiwar R., Soong N.W. and Punnonen J. | | DNA shuffling and vaccines | | Current Opinion in Molecular Therapeutics, February, 3(1): 31-36 | | |
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Year: 2000
| Author(s) |
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Title |
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Source |
| Powell S.K., Kaloss M.A., Pinkstaff A., McKee R., Burimski I., Pensiero M., Otto E., Stemmer W.P.C., and Soong N. -W. | | Breeding of retroviruses by DNA shuffling for improved stability and processing yields | | Nature Biotechnology, December 18(12): 1279-1282 | | | | Chang C-C.J., Wright A., and Punnonen J. | | Monocyte-derived CD1a+ and CD1a- dendritic cell subsets differ in their cytokine production profiles, susceptibilities to transfection, and capacities to direct Th cell differentiation | | Journal of Immunology, October 1, 165(7): 3584-3591 | | | | Punnonen J., Whalen R.G., Patten P.A., and Stemmer W.P.C. | | Molecular breeding by DNA shuffling | | Science & Medicine, March/April, 7(2): 38-47 | | | | Soong N.W., Nomura L., Pekrun K., Reed M., Sheppard L., Dawes G., and Stemmer W.P.C. | | Molecular breeding of viruses | | Nature Genetics, August, 25(4): 436-439 | | | | Punnonen J. (2000) | | Molecular breeding of allergy vaccines and antiallergic cytokines | | International Archives of Allergy and Immunology, March, 121(3): 173-182 | | |
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Year: 1999
| Author(s) |
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Title |
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Source |
| Stemmer W. P. C. and Soong, N.W. | | Molecular breeding of viruses for targeting and other clinical properties | | Tumor Targeting, July, 4(2): 59-62 | | |
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Year: 1998
Year: 1997
| Author(s) |
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Title |
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Source |
| Patten, P. A., Howard, R. J., and Stemmer, W.P.C. | | Applications of DNA shuffling to pharmaceuticals and vaccines | | Current Opinion in Biotechnology, December, 8(6): 724-733 | | |
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