PROTEIN ENGINEERING RESOURCES
Molecular breeding of genes creates recombinant DNA libraries containing millions of potential chimeric variants. Diversity is sourced by selection of phylogenetic homologs containing appropriate sequence content. Parent input genes are fragmented and assembled in correct coding order by in vitro homologous recombination over regions of overlapping identity.
Directed evolution of proteins parallels natural selection, whereby genetic variation is introduced into a population, environmental selective pressures are applied, and improvements in fitness are identified. Directed evolution is a key method of protein engineering for identifying novel protein variants that demonstrate desired character traits for specific applications.
DNA Shuffling and the Production of Novel Enzymes and Microorganisms for Effective Bioremediation and Biodegradation Process
Modifying Tropism of AAV with Molecular Breeding
Application of Molecular Breeding to Biocatalysis
Transcriptionally Active Polymerase Chain Reaction (TAP)